Directions to OIUF
355 Main Street
5 Cambridge Center, 8th Floor
Cambridge, MA 02142
Telephone Number: 617-494-1431
The entrance to 5 Cambridge Center is on Main Street. MERSI is located on the 8th floor. You will need to sign in at the security desk and provide your destination.
If you are using a GPS, please type in 80 Broadway in Cambridge, MA. This will take you to the Marriott Hotel and the garage entrance. After you park your car, be sure to exit the garage on the Main Street side.
Follow Rte. 3N or Rte. 95N to 1-93N. On 93N, take Exit 26, Storrow Drive West exit. Proceed onto Storrow Drive West. Get left and take first exit on left, Government Center/3N. Get in right lane and at end of ramp take right at light toward Cambridge/Memorial Drive. You will cross Longfellow Bridge onto Broadway Street. See directions below “from Broadway on back.”
Follow I-93S to Exit26 for Storrow Drive/North Station. Proceed onto Storrow Drive West. Get left and take first exit on left, Government Center/3N. Get in right lane and at end of ramp at light take right toward Cambridge/Memorial Drive. You will cross Longfellow Bridge onto Broadway Street. See directions below “from Broadway on back”.
Follow I-90 East (Mass Pike) to exit 18 Allston/Cambridge. Take the Allston/Cambridge exit toward Cambridge. Proceed onto Storrow Drive East into Boston. After 3 miles take the Government Center exit on right, stay left, and after the light, take an immediate left. You come to a traffic light, take a left at that light and cross over the Longfellow Bridge onto Broadway Street. See directions below “from Broadway on back.” Alternative directions to Storrow Drive, see Memorial Drive directions in “from Rt 2”.
From RT 2: Follow RTE 2 east into Cambridge and bear left onto Memorial Drive East. Travel 3 miles on Memorial Drive, take left at Kendall Square exit. Go straight through the set of lights onto Wadsworth St. and then, take your first, immediate left. Follow this street to the end and turn right onto Ames Street. Go straight at the first set of lights. You will see Legal Seafood's on the right and just after is the right turn into the Parking garage.
From Logan International Airport:
Follow signs through Sumner Tunnel to Rte. 93N. Then, follow directions above “from the South.”
You will come to a set of lights just after crossing over the bridge. The Marriot Hotel will be straight and on the left. Go straight through the lights, stay in left lane, and just after the Marriot Hotel front door is a left turn lane with nonfunctioning lights. Make a U-Turn here and get right. You will immediately see a sign on the right: Main St Westbound/ Marriot Service Entrance/Public Parking. At this sign, bear right and straight onto the cobblestone road that takes you into a U-Turn exiting onto Main St. Travel approximately 300 feet past the entrance to 5 Cambridge Center to a set of lights. At the lights, turn right onto Ames Street and 50 feet after Legal Seafood is the entrance on the right to the parking garage.
Subway directions: MBTA: Subway Schedule and Maps link
Take the Red Line to the Kendall Square/ MIT stop.
Exit onto Main Street.
Turn right and walk approximately 200 feet. The entrance to 5 Cambridge Center is on the right.
The Garage entrance on Ames Street should be open to MERSI patients despite any closure signs, however, you will need to use the intercom to announce yourself or other person as a MERSI patient. The garage attendant will instruct you from there. After parking the car, follow the signs to Main Street Elevators. Proceed to the first floor and exit out of the garage toward Main Street. The entrance to 5 Cambridge Center is approximately 25 feet on the right. It is directly across from MIT COOP.
MERSI Alternative Parking Directions
Easiest Way to Drop off at front door on Main Street:
Traveling on Broadway, after the first set of lights at the left turn lane, make a U-Turn and get right. You will immediately see a sign on the right: Main St Westbound/ Marriot Service Entrance. At this sign, bear right onto the cobblestone road (it doesn’t look like a public road, but it is) that takes you into a U-Turn exiting onto Main St. Travel approximately 200 feet and just after the MIT COOP is the entrance to 5 Cambridge Center.
Public Parking can be found at these 3 locations:
10 through 17 Cambridge Center:
At the set of lights just after crossing over the bridge, Go straight through two sets of lights. Approximately, 50 feet after the second set of lights (intersection of Ames and Broadway) will be a blue “P” for public parking. Take a right turn and the entrance is on the right. After parking the car, only use the Pedestrian Exit marked Broadway access to 10 and 11 Cambridge Center and Biogen Dec. Walk out to street and turn left to the first set of lights and cross street onto Ames Street. Proceed straight and just after Legal Seafood take a left onto Main Street. The entrance to 5 Cambridge Center is 25 feet on the left.
At the set of lights just after crossing over the bridge, take a right onto Third Street and on the right is a parking garage at One Broadway Center. After parking exit by foot onto third Street going left. At light cross Broadway Street and pass through the circular small park and take a right onto Main Street. Travel 250 feet to front door of 5 Cambridge Center.
At the set of lights just after crossing over the bridge, take a right onto Third Street and the first right onto Kendall Street just after One Broadway garage. Follow to the underground parking garage. This is a further walk than One Broadway garage. Proceed back to Third Street by foot and follow walking directions above.
Can be found on Main and Ames Street.